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Glossary
Semester (Sem)
1First Semester
2Second Semester
AAnnual course
Educational activities
CSimilar or integrative activities
Language
Course completely offered in italian
Course completely offered in english
--Not available
Innovative teaching
The credits shown next to this symbol indicate the part of the course CFUs provided with Innovative teaching.
These CFUs include:
  • Subject taught jointly with companies or organizations
  • Blended Learning & Flipped Classroom
  • Massive Open Online Courses (MOOC)
  • Soft Skills
Course Details
Context
Academic Year 2018/2019
School School of Industrial and Information Engineering
Name (Master of Science degree)(ord. 270) - MI (471) Biomedical Engineering
Track BCT - Ingegneria per cellule tessuti e biotecnologie - Cells, tissues and biotechnology
Programme Year 1

Course Details
ID Code 096269
Course Title BIOMOLECULES: STRUCTURE AND FUNCTIONS
Course Type Mono-Disciplinary Course
Credits (CFU / ECTS) 7.0
Semester First Semester
Course Description Objective of the course is the understanding at a molecular level of the structur-function relationship of biomolecules, limited to proteins and carbohydrates. Functional groups of biomolecules. Intermolecular interactions. Charged and neutral molecules. Hydrogen bond. Structural features conferring water solubility. Amino acids: natural, proteinogenic, non-natural. Acidity and basicity. pKa. Henderson-Hasselbach equation. Peptide bond. Peptide formation. Determination of peptides charge. Proteins: composition and structure. Chemical properties, electric charges. Primary structure. Higher organization levels. Folding and protein stability. Nature and role of non-covalent interactions. Inter- and intra-molecular bonds and biological properties. Cross-linking. Disulphide bonds. Methods to determineprotein structure. Structural and fibrous proteins. Collagen, elastin, cheratins, silk proteins. Miosine, actine movement. Molecular machines analogues of natural elastin. Globular proteins: mioglobine, hemoglonbine. Oxygen transport. Hill number. Bohr effect. Hb of type R- and T-. Sickle cell anemia. Structure activity relationship. Antibodies. Enzymes. Catalysis. Protein families with a commun catalytic mechanism: serine proteases. Enzyme kinetics. Inhibition. Regulation of enzymatic activity. Analitycal applications of enzymes. Enzyme classes and their application in clinical analysis. Hydrolases, lyases, ligases, kinases. Membrane proteins. Transport mechanism of charged or un-charged species. Active or passive transport. Aquaporin. Ionic channels. Reaction sequences using or producing energy. Thermodynamic of the transformation of high energy compounds. Polysaccharides as energy source. Carbohydrate metabolism. Glycolysis. Gluconeogenesis. Triglycerides metabolism. Synthesis and metabolism of amino acids.
Scientific-Disciplinary Sector (SSD)
Educational activities SSD Code SSD Description CFU
C
CHIM/07
PRINCIPLES OF CHEMISTRY FOR APPLIED TECHNOLOGIES
7.0

Schedule, add and removeAlphabetical groupProfessorLanguageCourse details
From (included)To (excluded)
--AZZZZFasoli Elisa
manifesti v. 3.1.3 / 3.1.3
Area Servizi ICT
20/10/2019