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Glossary
Semester (Sem)
1First Semester
2Second Semester
AAnnual course
Educational activities
BIdentifying activities
Language
Course completely offered in italian
Course completely offered in english
--Not available
Innovative teaching
The credits shown next to this symbol indicate the part of the course CFUs provided with Innovative teaching.
These CFUs include:
  • Subject taught jointly with companies or organizations
  • Blended Learning & Flipped Classroom
  • Massive Open Online Courses (MOOC)
  • Soft Skills
Degree ProgrammesCambia LinguaCambia Lingua
Course Details

Context
Academic Year 2018/2019
School School of Industrial and Information Engineering
Name (Master of Science degree)(ord. 270) - MI (471) Biomedical Engineering
Track BTE - Tecnologie elettroniche - Technologies for electronics
Programme Year 2

Course Details
ID Code 052381
Course Title BIOMOLECULAR MODELLING LABORATORY
Course Type Mono-Disciplinary Course
Credits (CFU / ECTS) 5.0
Semester First Semester
Course Description Molecular simulations are the theoretician's tools to understanding the fundamentals behind many physical and chemical phenomena. This course is designed to introduce the student to the theory and methodology behind these tools, and to expose the student to the power of molecular level simulations and modeling through practical applications. The aim of the course is to familiarize students with modern methods of biomolecular modelling. Both theoretical and computational activities will be developed. From the practical side the theoretical aspects will be used to study proteins, lipids, and saccharides and to address practical issues such as diffusion phenomena, determination of nanoscale mechanical properties, drug design, etc.). The main aspects covered in this course are: base concepts of molecular modelling approach; molecular mechanics, definition, features, and force field definition and parametrization; optimization techniques; molecular dynamics; coarse grain approach for biomolecules. In the laboratory activity students will be divided in groups and for each group a different project will be assigned. To complement the project activities and to stimulate active learning, the structuring skills of thinking and knowledge and the assessment among colleagues, each group of students is responsible for examining a specific topic that will be presented and discussed with other students in flipped/blended classroom modality. Students must acquire specific competences according with the following Dublin Descriptors: A: KNOWLEDGE AND UNDERSTANDING Knowledge and ability to discuss and present the main theoretical aspects presented in the course. Knowledge of the structure/function correlation in proteins. B: APPLYING KNOWLEDGE AND UNDERSTANDING Resolving problems and exercises in molecular modelling applying the correct mathematical models. Setting virtual experiments for characterization of proteins. C: INDIPENDENCE IN JUDGEMENT Critically analyzing the recent literature on molecular modeling and discussing results. D: COMUNICATION SKILLS Ability to present a paper of the most recent literature, the course is in english and students are encouraged to ask questions and discuss in English. The exam method consists of an written exam in which the students have to answer questions based on the material/theory taught during the lectures. The evaluation of the written part accounts for 2/3 of the final grade. 1/3 of the grade is based on the evaluation of the presentation given by each student in English on the project assigned during the course. It should be noted that this is a limited number access course. The mandatory procedure for access request is here: http://www.ccsbio.polimi.it/?page_id=27
Scientific-Disciplinary Sector (SSD)
Educational activities SSD Code SSD Description CFU
B
ING-IND/34
INDUSTRIAL BIOENGINEERING
5.0
Innovative teaching The course includes  1.0  credits in Innovative Teaching as follows:
  • Blended Learning & Flipped Classroom

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21/04/2019 Area Servizi ICT v. 2.11.10 / 2.11.10