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Information on didactic, research and institutional assignments on this page are certified by the University; more information, prepared by the professor, are available on the personal web page and in the curriculum vitae indicated on this webpage.
Information on professor
ProfessorRedaelli Alberto Cesare Luigi
QualificationFull professor
Belonging DepartmentDipartimento di Elettronica, Informazione e Bioingegneria
Scientific-Disciplinary SectorING-IND/34 - Industrial Bioengineering
Curriculum VitaeDownload CV (390.24Kb - 17/06/2019)
OrcIDhttps://orcid.org/0000-0002-9020-2188

Contacts
Professor's office hours
DepartmentFloorOfficeDayTimetableTelephoneFaxNotes
Elettronica, Informazione e Bioingegneria - Edificio 21----TuesdayFrom 09:15
To 12:00
3375--It's suggested to communicate by email the participation to the student hours
E-mailalberto.redaelli@polimi.it
Professor's personal websitehttp://www.biomech.polimi.it/people/redaelli.html

Data source: RE.PUBLIC@POLIMI - Research Publications at Politecnico di Milano

List of publications and reserach products for the year 2019 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Journal Articles
Molecular dynamics investigation of halogenated amyloidogenic peptides (Show >>)
A Simple Vacuum-Based Microfluidic Technique to Establish High-Throughput Organs-On-Chip and 3D Cell Cultures at the Microscale (Show >>)
Prothrombotic activity of cytokine-activated endothelial cells and shear-activated platelets in the setting of ventricular assist device support (Show >>)
Evaluation of 4D flow MRI-based non-invasive pressure assessment in aortic coarctations (Show >>)
Mixed impact of torsion on LV hemodynamics: A CFD study based on the Chimera technique (Show >>)
A Novel Multiparametric Score for the Detection and Grading of Prosthetic Mitral Valve Obstruction in Cases With Different Disc Motion Abnormalities (Show >>)
A novel hybrid silk-fibroin/polyurethane three-layered vascular graft: Towards in situ tissue-engineered vascular accesses for haemodialysis (Show >>)
Blood damage in Left Ventricular Assist Devices: Pump thrombosis or system thrombosis? (Show >>)
Aortic flow after valve sparing root replacement with or without neosinuses reconstruction (Show >>)
Shear-mediated platelet activation enhances thrombotic complications in patients with LVADs and is reversed after heart transplantation (Show >>)
Fluid-Structure Interaction and In Vitro Analysis of a Real Bileaflet Mitral Prosthetic Valve to Gain Insight Into Doppler-Silent Thrombosis (Show >>)
Aortic Root Dynamics in Sleeve Aortic Sparing Procedure: Echocardiographic and Computational Studies (Show >>)
Immediate Impact of Prosthetic Graft Replacement of the Ascending Aorta on Circumferential Strain in the Descending Aorta (Show >>)
Noise of open and semi-closed bileaflet prosthetic mitral valve (Show >>)
Conference proceedings
Approach For Cardiac Action Potential Detection From Noised Recordings (Show >>)
Differentiation of the 4D MRI blood flow data to estimate the vorticity and shear stress in aorta, pulmonary artery and the heart (Show >>)
Patents
METHODS , DEVICES , AND SYSTEMS FOR MICROFLUIDIC STRESS EMULATION (Show >>)
Microfluidic device and relative method for the generation and/or culture and/or maturation of three- dimensional cell and/or tissue constructs (Show >>)


List of publications and reserach products for the year 2018 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Journal Articles
Thermal stabilization of the deglycating enzyme Amadoriase i by rational design (Show >>)
Review: Engineering of thermostable enzymes for industrial applications (Show >>)
Novel insights by 4D Flow imaging on aortic flow physiology after valve-sparing root replacement with or without neosinuses (Show >>)
Experimental quantification of the fluid dynamics in blood-processing devices through 4D-flow imaging: A pilot study on a real oxygenator/heat-exchanger module (Show >>)
Routine clinical anti-platelet agents have limited efficacy in modulating hypershear-mediated platelet activation associated with mechanical circulatory support (Show >>)
Design and validation of a microfluidic device for blood–brain barrier monitoring and transport studies (Show >>)
Hydrodynamic and Geometric Behavior of Two Pericardial Prostheses Implanted in Small Aortic Roots (Show >>)
Platelet activation is a preoperative risk factor for the development of thromboembolic complications in patients with continuous-flow left ventricular assist device (Show >>)
A Computational Model of Electrophysiological Properties of Cardiomyocytes (Show >>)
Microfluidic flow-based platforms for induction and analysis of dynamic shear-mediated platelet activation - Initial validation versus the standardized hemodynamic shearing device (Show >>)
TCT-17 Tricuspid Valve Regurgitation Reduction Following Concomitant Subvalvular and Annulus-level Treatment – Ex-vivo Study (Show >>)
A microscale biomimetic platform for generation and electro-mechanical stimulation of 3D cardiac microtissues (Show >>)
An experimental and computational study of the inferior vena cava hemodynamics under respiratory-induced collapse of the infrarenal IVC (Show >>)
Prediction of stenting related adverse events through patient-specific finite element modelling (Show >>)
Abstract in Rivista
Development of an organotypic microfluidic model to reproduce monocyte extravasation process in the osteoarthritic joint (Show >>)
RIGHT VENTRICULAR PAPILLARY MUSCLES APPROXIMATION: INSIGHT FROM EX VIVO FUNCTIONAL TRUCISPID REGURGITATION MODEL (Show >>)
Conference proceedings
One-dimensional Models for Cell Feeding in Micro-channels. (Show >>)
Computer modelling of cardiac cells electrical activity (Show >>)
Abstract in Atti di convegno
Towards the exhaustive analysis of left ventricle dysfunctions in ischemic cardiomyopathy: integrating MR-derived wall kinetics, scar transmurality and fluid dynamics (Show >>)
Tricuspid valve transcatheter treatments assessment in a passive beating heart platform (Show >>)
A novel imaged-based approach for tricuspid valve biomechanical evaluation through finite element modelling (Show >>)
In-vitro three-dimensional hemodynamic mapping of surgically implanted pericardial valves through 4D Flow MRI. (Show >>)
Quantification of the Aortic Hemodynamicsafter Transcatheter Aortic Valve Implantation Combining 3d-Printing, 4d PC-MRI and Computational Fluid Dynamics (Show >>)
4D-Flow MRI based non-invasive hemodynamic assessment and diagnosis in aortic coarctations (Show >>)
Patents
SYSTEMS AND METHODS FOR ANALYZING PLATELET FUNCTION (Show >>)


List of publications and reserach products for the year 2017 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Journal Articles
Towards the improved quantification of in vivo abnormal wall shear stresses in BAV-affected patients from 4D-flow imaging: Benchmarking and application to real data (Show >>)
In vitro and in silico approaches to quantify the effects of the Mitraclip® system on mitral valve function (Show >>)
A novel approach to the quantification of aortic root in vivo structural mechanics (Show >>)
Aortic Root Biomechanics After Sleeve And David Sparing Techniques: A Finite Element Analysis (Show >>)
Generating Multicompartmental 3D Biological Constructs Interfaced through Sequential Injections in Microfluidic Devices (Show >>)
Nanostructure and stability of calcitonin amyloids (Show >>)
Mass-spring models for the simulation of mitral valve function: Looking for a trade-off between reliability and time-efficiency (Show >>)
4D flow analysis of BAV-Related fluid-dynamic alterations: Evidences of wall shear stress alterations in absence of clinically-relevant aortic anatomical remodeling (Show >>)
Dynamic and quantitative evaluation of degenerative mitral valve disease: A dedicated framework based on cardiac magnetic resonance imaging (Show >>)
High Frequency Components of Hemodynamic Shear Stress Profiles are a Major Determinant of Shear-Mediated Platelet Activation in Therapeutic Blood Recirculating Devices (Show >>)
Microfludic platforms for the evaluation of anti-platelet agent efficacy under hyper-shear conditions associated with ventricular assist devices (Show >>)
Special Issue “Micro and Nano Flows 2016 (MNF2016) – Biomedical Stream” (Show >>)
Toward the virtual benchmarking of pneumatic ventricular assist devices: application of a novel fluid–structure interaction-based strategy to the Penn State 12 cc device (Show >>)
Systolic anterior motion after mitral valve repair: A predictive computational model (Show >>)
Recensioni su riviste
Tailoring cardiac environment in microphysiological systems: an outlook on current and perspective heart-on-chip platforms (Show >>)
Abstract in Rivista
Modelling of 3D spatially controlled compartmentalized tissues in microfluidics (Show >>)
Conference proceedings
Analitical and numerical simulation of platelets in microchannels and their stress history (Show >>)
Patents
TEST BENCH ASSEMBLY FOR THE SIMULATION OF CARDIAC SURGERY AND/OR INTERVENTIONAL CARDIOLOGY OPERATIONS (Show >>)
THERMOSTABILIZED AMADORIASES AND USES THEREOF (Show >>)
Three-dimensional multilayer constructs in microchannels (Show >>)


List of publications and reserach products for the year 2016 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Journal Articles
Design of a microfluidic strategy for trapping and screening single cells (Show >>)
Beating heart on a chip: a novel microfluidic platform to generate functional 3D cardiac microtissues (Show >>)
In vitro assessment of mitral valve function in cyclically pressurized porcine hearts (Show >>)
On the Use of the Platelet Activity State Assay for the In Vitro Quantification of Platelet Activation in Blood Recirculating Devices for Extracorporeal Circulation (Show >>)
Microfluidic approaches for the assessment of blood cell trauma: a focus on thrombotic risk in mechanical circulatory support devices (Show >>)
Transcatheter Edge-to-Edge Treatment of Functional Tricuspid Regurgitation in an Ex Vivo Pulsatile Heart Model (Show >>)
Comparison of the Performance of a Sutureless Bioprosthesis With Two Pericardial Stented Valves on Small Annuli: An In Vitro Study (Show >>)
Opening–closing pattern of four pericardial prostheses: results from an in vitro study of leaflet kinematics (Show >>)
Impact of different aortic valve calcification patterns on the outcome of transcatheter aortic valve implantation: A finite element study (Show >>)
Aspirin has limited ability to modulate shear-mediated platelet activation associated with elevated shear stress of ventricular assist devices (Show >>)
Microfabricated Physiological Models for In Vitro Drug Screening Applications (Show >>)
Molecular dynamics simulations provide insights into the substrate specificity of FAOX family members (Show >>)
Advanced glycation end-products: Mechanics of aged collagen from molecule to tissue (Show >>)
Abstract in Rivista
Towards a more accurate planning of invasive procedures: finite element simulation of percutaneous pulmonary valve implantation (Show >>)
Abstract in Atti di convegno
A microfluidic device for studying drug transport through endothelial Blood Brain Barrier cells monolayers (Show >>)
Patents
Assieme di banco prova per la simulazione di interventi di cardiochirurgia e/o procedure di cardiologia interventistica (Show >>)
Costrutti tridimensionali multistrato in microcanali (Show >>)
Microfluidic device and relative method for the generation and/or culture and/or maturation of three-dimensional cells and/or tissue constructs (Show >>)


List of publications and reserach products for the year 2015 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Journal Articles
High-Throughput Microfluidic Platform for 3D Cultures of Mesenchymal Stem Cells, Towards Engineering Developmental Processes (Show >>)
Influence of the aortic valve leaflets on the fluid-dynamics in aorta in presence of a normally functioning bicuspid valve (Show >>)
High-throughput microfluidic platform for adherent single cells non-viral gene delivery (Show >>)
Fluid-dynamic results of in vitro comparison of four pericardial bioprostheses implanted in small porcine aortic roots. (Show >>)
Does the type of suture technique affect the fluid-dynamic performance of bioprostheses implanted in small aortic roots? Results from an in vitro study. (Show >>)
A novel passive left heart platform for device testing and research. (Show >>)
Hemodynamic and thrombogenic analysis of a trileaflet polymeric valve using a fluid-structure interaction approach (Show >>)
Lab-on-Chip for testing myelotoxic effect of drugs and chemicals (Show >>)
An anatomy-based lumped parameter model of cerebrospinal venous circulation: Can an extracranial anatomical change impact intracranial hemodynamics? (Show >>)
Biomechanical drawbacks of different techniques of mitral neochordal implantation: When an apparently optimal repair can fail (Show >>)
Functional and Biomechanical Effects of the Edge-to-Edge Repair in the Setting of Mitral Regurgitation: Consolidated Knowledge and Novel Tools to Gain Insight into Its Percutaneous Implementation (Show >>)
A numerical performance assessment of a commercial cardiopulmonary by-pass blood heat exchanger (Show >>)
Microfluidic emulation of mechanical circulatory support device shear-mediated platelet activation (Show >>)
A Model of Health: Mathematical modeling tools play an important role in optimizing new treatment options for heart disease (Show >>)
A Comprehensive Fluid Dynamic and Geometric Study for an “ In-Vitro ” Comparison of Four Surgically Implanted Pericardial Stented Valves (Show >>)
Contributions on scientific books
Repair of Mitral Valve Prolapse Through ePTFE Neochordae: A Finite Element Approach From CMR (Show >>)
The Principle: From a Computational Model to Clinical Validation (Show >>)
Finite Element Analysis of Transcatheter Aortic Valve Implantation in the Presence of Aortic Leaflet Calcifications (Show >>)
Conference proceedings
Phase contrast MRI: Development of a user-friendly platform for fast-automated segmentation and fluid-dynamic post-processing (Show >>)
Shear-mediated platelet activation in patients implanted with continuous flow LVADs: A preliminary study utilizing the platelet activity state (PAS) assay. (Show >>)
Abstract in Atti di convegno
Towards modeling limb development: high-throughput microfluidic platform for culturing mesenchymal stromal cell perfused micromasses (Show >>)
Thromboembolic complications after left ventricular assist device implantation is associated with platelet activation as measured via the Platelet Activity State assay (Show >>)
A combined multiscale numerical and experimental approach for the design optimization of hollow-fiber based medical devices (Show >>)
Microfluidic facsimile of ventricular assist device shear stress patterns: towards point-of-care devices to monitor patient thrombotic risk (Show >>)
Patents
Methods, devices, and systems for microfluidic stress emulation (Show >>)
Dispositivo microfluidico e relativo metodo per la generazione e/o la coltivazione e/o la maturazione di costrutti cellulari e/o tissutali tridimensionali (Show >>)
manifesti v. 3.1.9 / 3.1.9
Area Servizi ICT
07/12/2019