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Information on professor
ProfessorRedaelli Alberto Cesare Luigi
QualificationFull professor
Belonging DepartmentDipartimento di Elettronica, Informazione e Bioingegneria
Scientific-Disciplinary SectorING-IND/34 - Industrial Bioengineering
Curriculum VitaeDownload CV (390.24Kb - 17/06/2019)

Professor's office hours
Elettronica, Informazione e Bioingegneria - Edificio 21----TuesdayFrom 09:15
To 12:00
3375--It's suggested to communicate by email the participation to the student hours
Professor's personal websitehttp://www.biomech.polimi.it/people/redaelli.html

Data source: RE.PUBLIC@POLIMI - Research Publications at Politecnico di Milano

List of publications and reserach products for the year 2019 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Journal Articles
Molecular dynamics investigation of halogenated amyloidogenic peptides (Show >>)
A Simple Vacuum-Based Microfluidic Technique to Establish High-Throughput Organs-On-Chip and 3D Cell Cultures at the Microscale (Show >>)
Prothrombotic activity of cytokine-activated endothelial cells and shear-activated platelets in the setting of ventricular assist device support (Show >>)
Evaluation of 4D flow MRI-based non-invasive pressure assessment in aortic coarctations (Show >>)
Mixed impact of torsion on LV hemodynamics: A CFD study based on the Chimera technique (Show >>)
A Novel Multiparametric Score for the Detection and Grading of Prosthetic Mitral Valve Obstruction in Cases With Different Disc Motion Abnormalities (Show >>)
A novel hybrid silk-fibroin/polyurethane three-layered vascular graft: Towards in situ tissue-engineered vascular accesses for haemodialysis (Show >>)
Blood damage in Left Ventricular Assist Devices: Pump thrombosis or system thrombosis? (Show >>)
Aortic flow after valve sparing root replacement with or without neosinuses reconstruction (Show >>)
Shear-mediated platelet activation enhances thrombotic complications in patients with LVADs and is reversed after heart transplantation (Show >>)
Fluid-Structure Interaction and In Vitro Analysis of a Real Bileaflet Mitral Prosthetic Valve to Gain Insight Into Doppler-Silent Thrombosis (Show >>)
Aortic Root Dynamics in Sleeve Aortic Sparing Procedure: Echocardiographic and Computational Studies (Show >>)
Immediate Impact of Prosthetic Graft Replacement of the Ascending Aorta on Circumferential Strain in the Descending Aorta (Show >>)
Noise of open and semi-closed bileaflet prosthetic mitral valve (Show >>)
Conference proceedings
Approach For Cardiac Action Potential Detection From Noised Recordings (Show >>)
Differentiation of the 4D MRI blood flow data to estimate the vorticity and shear stress in aorta, pulmonary artery and the heart (Show >>)
Microfluidic device and relative method for the generation and/or culture and/or maturation of three- dimensional cell and/or tissue constructs (Show >>)

List of publications and reserach products for the year 2018 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Journal Articles
Thermal stabilization of the deglycating enzyme Amadoriase i by rational design (Show >>)
Review: Engineering of thermostable enzymes for industrial applications (Show >>)
Novel insights by 4D Flow imaging on aortic flow physiology after valve-sparing root replacement with or without neosinuses (Show >>)
Experimental quantification of the fluid dynamics in blood-processing devices through 4D-flow imaging: A pilot study on a real oxygenator/heat-exchanger module (Show >>)
Routine clinical anti-platelet agents have limited efficacy in modulating hypershear-mediated platelet activation associated with mechanical circulatory support (Show >>)
Design and validation of a microfluidic device for blood–brain barrier monitoring and transport studies (Show >>)
Hydrodynamic and Geometric Behavior of Two Pericardial Prostheses Implanted in Small Aortic Roots (Show >>)
Platelet activation is a preoperative risk factor for the development of thromboembolic complications in patients with continuous-flow left ventricular assist device (Show >>)
A Computational Model of Electrophysiological Properties of Cardiomyocytes (Show >>)
Microfluidic flow-based platforms for induction and analysis of dynamic shear-mediated platelet activation - Initial validation versus the standardized hemodynamic shearing device (Show >>)
TCT-17 Tricuspid Valve Regurgitation Reduction Following Concomitant Subvalvular and Annulus-level Treatment – Ex-vivo Study (Show >>)
A microscale biomimetic platform for generation and electro-mechanical stimulation of 3D cardiac microtissues (Show >>)
An experimental and computational study of the inferior vena cava hemodynamics under respiratory-induced collapse of the infrarenal IVC (Show >>)
Prediction of stenting related adverse events through patient-specific finite element modelling (Show >>)
Abstract in Rivista
Development of an organotypic microfluidic model to reproduce monocyte extravasation process in the osteoarthritic joint (Show >>)
Conference proceedings
One-dimensional Models for Cell Feeding in Micro-channels. (Show >>)
Computer modelling of cardiac cells electrical activity (Show >>)
Abstract in Atti di convegno
Towards the exhaustive analysis of left ventricle dysfunctions in ischemic cardiomyopathy: integrating MR-derived wall kinetics, scar transmurality and fluid dynamics (Show >>)
Tricuspid valve transcatheter treatments assessment in a passive beating heart platform (Show >>)
A novel imaged-based approach for tricuspid valve biomechanical evaluation through finite element modelling (Show >>)
In-vitro three-dimensional hemodynamic mapping of surgically implanted pericardial valves through 4D Flow MRI. (Show >>)
Quantification of the Aortic Hemodynamicsafter Transcatheter Aortic Valve Implantation Combining 3d-Printing, 4d PC-MRI and Computational Fluid Dynamics (Show >>)
4D-Flow MRI based non-invasive hemodynamic assessment and diagnosis in aortic coarctations (Show >>)

List of publications and reserach products for the year 2017 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Journal Articles
Towards the improved quantification of in vivo abnormal wall shear stresses in BAV-affected patients from 4D-flow imaging: Benchmarking and application to real data (Show >>)
In vitro and in silico approaches to quantify the effects of the Mitraclip® system on mitral valve function (Show >>)
A novel approach to the quantification of aortic root in vivo structural mechanics (Show >>)
Aortic Root Biomechanics After Sleeve And David Sparing Techniques: A Finite Element Analysis (Show >>)
Generating Multicompartmental 3D Biological Constructs Interfaced through Sequential Injections in Microfluidic Devices (Show >>)
Nanostructure and stability of calcitonin amyloids (Show >>)
Mass-spring models for the simulation of mitral valve function: Looking for a trade-off between reliability and time-efficiency (Show >>)
4D flow analysis of BAV-Related fluid-dynamic alterations: Evidences of wall shear stress alterations in absence of clinically-relevant aortic anatomical remodeling (Show >>)
Dynamic and quantitative evaluation of degenerative mitral valve disease: A dedicated framework based on cardiac magnetic resonance imaging (Show >>)
High Frequency Components of Hemodynamic Shear Stress Profiles are a Major Determinant of Shear-Mediated Platelet Activation in Therapeutic Blood Recirculating Devices (Show >>)
Microfludic platforms for the evaluation of anti-platelet agent efficacy under hyper-shear conditions associated with ventricular assist devices (Show >>)
Special Issue “Micro and Nano Flows 2016 (MNF2016) – Biomedical Stream” (Show >>)
Toward the virtual benchmarking of pneumatic ventricular assist devices: application of a novel fluid–structure interaction-based strategy to the Penn State 12 cc device (Show >>)
Systolic anterior motion after mitral valve repair: A predictive computational model (Show >>)
Recensioni su riviste
Tailoring cardiac environment in microphysiological systems: an outlook on current and perspective heart-on-chip platforms (Show >>)
Abstract in Rivista
Modelling of 3D spatially controlled compartmentalized tissues in microfluidics (Show >>)
Conference proceedings
Analitical and numerical simulation of platelets in microchannels and their stress history (Show >>)
Three-dimensional multilayer constructs in microchannels (Show >>)

List of publications and reserach products for the year 2016 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Journal Articles
Design of a microfluidic strategy for trapping and screening single cells (Show >>)
Beating heart on a chip: a novel microfluidic platform to generate functional 3D cardiac microtissues (Show >>)
In vitro assessment of mitral valve function in cyclically pressurized porcine hearts (Show >>)
On the Use of the Platelet Activity State Assay for the In Vitro Quantification of Platelet Activation in Blood Recirculating Devices for Extracorporeal Circulation (Show >>)
Microfluidic approaches for the assessment of blood cell trauma: a focus on thrombotic risk in mechanical circulatory support devices (Show >>)
Transcatheter Edge-to-Edge Treatment of Functional Tricuspid Regurgitation in an Ex Vivo Pulsatile Heart Model (Show >>)
Comparison of the Performance of a Sutureless Bioprosthesis With Two Pericardial Stented Valves on Small Annuli: An In Vitro Study (Show >>)
Opening–closing pattern of four pericardial prostheses: results from an in vitro study of leaflet kinematics (Show >>)
Impact of different aortic valve calcification patterns on the outcome of transcatheter aortic valve implantation: A finite element study (Show >>)
Aspirin has limited ability to modulate shear-mediated platelet activation associated with elevated shear stress of ventricular assist devices (Show >>)
Microfabricated Physiological Models for In Vitro Drug Screening Applications (Show >>)
Molecular dynamics simulations provide insights into the substrate specificity of FAOX family members (Show >>)
Advanced glycation end-products: Mechanics of aged collagen from molecule to tissue (Show >>)
Abstract in Rivista
Towards a more accurate planning of invasive procedures: finite element simulation of percutaneous pulmonary valve implantation (Show >>)
Abstract in Atti di convegno
A microfluidic device for studying drug transport through endothelial Blood Brain Barrier cells monolayers (Show >>)
Assieme di banco prova per la simulazione di interventi di cardiochirurgia e/o procedure di cardiologia interventistica (Show >>)
Costrutti tridimensionali multistrato in microcanali (Show >>)
Microfluidic device and relative method for the generation and/or culture and/or maturation of three-dimensional cells and/or tissue constructs (Show >>)

List of publications and reserach products for the year 2015 (Show all details | Hide all details)
Type Title of the Publicaiton/Product
Journal Articles
High-Throughput Microfluidic Platform for 3D Cultures of Mesenchymal Stem Cells, Towards Engineering Developmental Processes (Show >>)
Influence of the aortic valve leaflets on the fluid-dynamics in aorta in presence of a normally functioning bicuspid valve (Show >>)
High-throughput microfluidic platform for adherent single cells non-viral gene delivery (Show >>)
Fluid-dynamic results of in vitro comparison of four pericardial bioprostheses implanted in small porcine aortic roots. (Show >>)
Does the type of suture technique affect the fluid-dynamic performance of bioprostheses implanted in small aortic roots? Results from an in vitro study. (Show >>)
A novel passive left heart platform for device testing and research. (Show >>)
Hemodynamic and thrombogenic analysis of a trileaflet polymeric valve using a fluid-structure interaction approach (Show >>)
Lab-on-Chip for testing myelotoxic effect of drugs and chemicals (Show >>)
An anatomy-based lumped parameter model of cerebrospinal venous circulation: Can an extracranial anatomical change impact intracranial hemodynamics? (Show >>)
Biomechanical drawbacks of different techniques of mitral neochordal implantation: When an apparently optimal repair can fail (Show >>)
Functional and Biomechanical Effects of the Edge-to-Edge Repair in the Setting of Mitral Regurgitation: Consolidated Knowledge and Novel Tools to Gain Insight into Its Percutaneous Implementation (Show >>)
A numerical performance assessment of a commercial cardiopulmonary by-pass blood heat exchanger (Show >>)
Microfluidic emulation of mechanical circulatory support device shear-mediated platelet activation (Show >>)
A Model of Health: Mathematical modeling tools play an important role in optimizing new treatment options for heart disease (Show >>)
A Comprehensive Fluid Dynamic and Geometric Study for an “ In-Vitro ” Comparison of Four Surgically Implanted Pericardial Stented Valves (Show >>)
Contributions on scientific books
Repair of Mitral Valve Prolapse Through ePTFE Neochordae: A Finite Element Approach From CMR (Show >>)
The Principle: From a Computational Model to Clinical Validation (Show >>)
Finite Element Analysis of Transcatheter Aortic Valve Implantation in the Presence of Aortic Leaflet Calcifications (Show >>)
Conference proceedings
Phase contrast MRI: Development of a user-friendly platform for fast-automated segmentation and fluid-dynamic post-processing (Show >>)
Shear-mediated platelet activation in patients implanted with continuous flow LVADs: A preliminary study utilizing the platelet activity state (PAS) assay. (Show >>)
Abstract in Atti di convegno
Towards modeling limb development: high-throughput microfluidic platform for culturing mesenchymal stromal cell perfused micromasses (Show >>)
Thromboembolic complications after left ventricular assist device implantation is associated with platelet activation as measured via the Platelet Activity State assay (Show >>)
A combined multiscale numerical and experimental approach for the design optimization of hollow-fiber based medical devices (Show >>)
Microfluidic facsimile of ventricular assist device shear stress patterns: towards point-of-care devices to monitor patient thrombotic risk (Show >>)
Methods, devices, and systems for microfluidic stress emulation (Show >>)
Dispositivo microfluidico e relativo metodo per la generazione e/o la coltivazione e/o la maturazione di costrutti cellulari e/o tissutali tridimensionali (Show >>)
manifesti v. 3.1.9 / 3.1.9
Area Servizi ICT